A simple explanation of the Heisenberg Uncertainty Principle goes as follows:
You have a particle that you are trying to find out where it is an how fast it is moving. You are taking measurements by shining a laser onto it. If you want more accuracy on the location then you can shine a brighter laser. However this changes the velocity. If you want a more precise velocity then you need to use a dimmer laser. There is a finite limit to the combined accuracy or position and velocity.
There is a similar problem with projects that are deemed late. Frequently the solution is to add more frequent and intensive status reports. The problem is the addition of the status report takes away time that could be spent working so it will actually delay the result. In extreme cases the project will then never be finished as all time is taken up by reporting.
Developer Rants 